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Adrenal Insufficiency Revealing Bilateral Adrenal Metastasis of a Lung Cancer: A Case Report

Year: 2025

Type: article

Abstract: Adrenal insufficiency is a rare complication of adrenal metastasis and can be the first clinical manifestation of an underlying malignancy.Herein we report the case of a 34-yearsold male, with a history of heavy smoking, who presented to the emergency department after experiencing several weeks of weakness, rapid weight loss, skin pigmentation.The biological workup performed in emergency was in favor of adrenal insufficiency.The etiological investigation revealed a large lung mass which, after biopsy, turned out to be a lung adenocarcinoma.The lung cancer subsequently caused adrenal metastasis and therefore adrenal insufficiency.This case highlights the importance of considering adrenal metastasis as a possible cause of adrenal insufficiency in patients with a history of malignancy.

Source: Journal of Endocrine Surgery

DOI: 10.16956/jes.2025.25.2.85

Authors: Salma Wahbi, Samia Bentaleb, Hayat Aynaou, Houda Salhi

Institutions: Centre Hospitalier Universitaire Hassan II, Sidi Mohamed Ben Abdellah University

Language: English

Topic: Adrenal Hormones and Disorders

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4411825349