Work

Bioorthogonal activation and mitochondrial targeting of a near-infrared-emitting iridium( iii ) nitrone complex via cyclooctynylated phosphonium cations for enhanced cellular imaging and photodynamic therapy

Year: 2025

Type: article

Abstract: In this work, we present the bioorthogonal activation and mitochondria targeting of a near-infrared-emitting iridium( iii ) nitrone complex via cyclooctynylated phosphonium cations for enhanced cellular imaging and photodynamic therapy.

Source: Inorganic Chemistry Frontiers

DOI: 10.1039/d5qi01139f

Authors: Edward R. H. Walter, Lawrence Cho-Cheung Lee, Peter Kam-Keung Leung, Kenneth Kam-Wing Lo, Nicholas J. Long

Institutions: Imperial College London, City University of Hong Kong

Language: English

Topic: Metal complexes synthesis and properties

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

Open Access status: hybrid

Funders: Innovation and Technology Commission, Hong Kong Government

OpenAlex ID: W4411864766

FWCI: 1.862

Cites: 80

Cited by: 5

Related to: 10