Physical Activity is Associated with Improved Glycemic Outcomes in Newly Diagnosed Youth with Type 1 Diabetes: 4T Exercise Program
Year: 2025
Type: other
Abstract: Objective: The 4T Exercise Program evaluated physical activity patterns across the first year of type 1 diagnosis and whether physical activity was associated with changes in glucose outcomes in the 24-hours following physical activity. Research Design and Methods: The 4T Exercise Program started newly diagnosed youth with type 1 diabetes on a continuous glucose monitoring (CGM) system and physical activity tracker around 1-month post-diagnosis. A subset of youth opted to participate in up to four quarterly structured exercise education sessions to increase their knowledge around safe physical activity. Results: Ninety-eight youth with type 1 diabetes (median [IQR] age of 13 [12-15] years, 45% female, 44% Non-Hispanic White) completed the study. Compared to sedentary days, days with ≥10 mins of vigorous-intensity physical activity were associated with an increase in time in range (TIR) by 2.3% (1.4-3.2%; p<0.001), decrease in time above range (TAR) by 3.1% (2.2-4.0%; p<0.001), and increase in time below range (TBR) by 0.8% (0.6-0.9%; p<0.001) in the 24 hours following physical activity. From 1-3 months to 10-12 months post-diagnosis, the median (IQR) step count increased by 1,134 (445-1,519) steps per day (p<0.001), while daily moderate-to-vigorous physical activity (MVPA) increased by 11 (2-23) mins per day (p<0.001). Conclusions: In the 24-hours following physical activity as compared to sedentary days, TIR improved, TAR was lower, and TBR remained within clinical target recommendations. For youth with new onset type 1 diabetes, each structured exercise education session was associated a further 0.79% increase in TIR.
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4411878853