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Association of midlife hearing impairment and hearing aid use with incident dementia: analysis of two UK-based longitudinal cohort studies

Year: 2025
Type: article
Study design: Observational Study
Abstract: The prevalence of hearing impairment and dementia increases with age but the nature of their association remains unclear. Using data from two large UK-based cohort studies, we examined the longitudinal association of 'midlife' hearing impairment and hearing aid use with incident dementia. We found modest associations and population attributable fractions for reported and measured 'midlife' hearing impairment, highlighting the need to consider age at measurement of risk factors in studies that target dementia prevention.
Source: Nature Aging
DOI: 10.1038/s43587-025-00914-1
Authors: Marcos D. Machado-Fragua, Aurore Fayosse, Julien Dumurgier, Mika Kivimaki, Céline Ben Hassen, Gill Livingston, Claire Paquet, Séverine Sabia, Archana Singh-Manoux
Institutions: Inserm, Université Paris Cité, Equipe de Recherche en Epidémiologie Nutritionnelle, Centre de Recherche Épidémiologie et Statistique, Assistance Publique – Hôpitaux de Paris, Hôpital Fernand-Widal, University College London
Language: English
Open Access status: hybrid
Estimated APC paid: $12,690
Funders: Wellcome Trust, British Heart Foundation, Agence Nationale de la Recherche, Academy of Finland, Northwest Regional Development Agency, National Institutes of Health, Medical Research Council, National Institute on Aging, HORIZON EUROPE European Research Council
Awards: G1190173965, G1787587971, Effects of stress on the development of Alzheimer's disease and other dementias, G2170486216, G2283396561, Circadian rhythm: from preclinical to post-diagnosis dementia, G3091909500, Role of mid- and late-life risk factors in social inequalities in Alzheimer's Disease and Related Dementias, G3816174250, Education, socioeconomic status and Aging: transitions from multimorbidity to functional limitations and mortality, Taking the long view: Identification of plasma protein biomarkers for dementia risk, A social, economic and mathematical approach to autonomy in ageing, Taking the long view: Identification of plasma protein biomarkers for dementia risk, G5001906568, G5676749234, G6252682278, G7189585906, G8337390295, G84288707, G9000219096
OpenAlex ID: W4411900422
FWCI: 2.211
Cites: 31
Cited by: 4
Related to: 10