High-frequency quantitative ultrasound in characterizing human skin aging: an exploration of the non-modeling and modeling approaches
Year: 2025
Type: article
Study design: Observational Study
Abstract: Background: High-frequency quantitative ultrasound (HQUS) technology, with its non-invasiveness, high-resolution, objectivity, and reproducibility, holds significant potential for characterizing skin aging through the analysis of the internal structure of tissues. This study aims to explore a framework for characterizing skin aging assessment through HQUS technology to facilitate the subsequent analysis of skin aging-related studies. Methods: ) at scanning depths of 1 and 1.5 mm, respectively, and discovered that such a characterization framework is well-suitable for quantifying skin aging. These parameters were calculated based on ultrasound backscattered signals at a high frequency of 42 MHz from the facial skin (from the epidermis to the dermis) of 70 female participants aged 24-57 years and then analyzed using the linear fitting and receiver operating characteristic (ROC) curves. Results: also has the highest area under the curve among the ROC curves, regardless of the scanning depth. Conclusions: , has great feasibility for the characterization of human skin aging. The proposed framework holds significant potential for assessing the efficacy of facial rejuvenation products, photofacials, and similar treatments.
Authors: Yuzhen Li, Bingbing He, Xun Lang, Guang Shi, Ningtao Zhang, Zhenyu Guo, Yufeng Zhang
Institutions: Yunnan University, Yunnan Botanee Biotechnology Group Co.
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4411901814