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The efficacy of remote ischemic conditioning in improving neurological function and short-term prognosis in acute ischemic stroke: a prospective controlled study

Year: 2025

Type: article

Abstract: Objective: To evaluate the efficacy of remote ischemic conditioning (RIC) in improving neurological function and short-term prognosis in patients with acute ischemic stroke (AIS). Methods: = 199). RIC was administered manually using a cuff sphygmomanometer, while the control group received a sham RIC treatment. Patients with cardioembolic sources or a history of prior stroke were excluded from the study. Primary outcomes were the proportion of patients with an mRS score of ≤2 at 7 days, as well as changes in the National Institutes of Health Stroke Scale (NIHSS), modified Rankin Scale (mRS), Activities of Daily Living (ADL), and Rancho Los Amigos (RLA) scores. Data were collected at baseline and 7 days post-enrollment, with in-person follow-up visits conducted by blinded clinicians. Results: > 0.05). Binary Logistic Regression Analysis indicated that, after adjusting for baseline factors, the treatment effect of RIC remained statistically significant. Conclusion: RIC treatment enhances neurological function and improves short-term prognosis in AIS patients. These findings support the potential clinical application of RIC in AIS management.

Source: Frontiers in Neurology

DOI: 10.3389/fneur.2025.1542833

Authors: Peiqi Huang, Kun Lin, Liling Wei, Qiong Zeng

Institutions: First Affiliated Hospital of Shantou University Medical College, Shantou University

Language: English

Topic: Acute Ischemic Stroke Management

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801