Study on the extraction of flavonoids from Artemisia integrifolia and its anti-lung cancer activity
Year: 2025
Type: conference-paper
Abstract: Objective: To extract flavonoids from Artemisia integrifolia and determine their content, to evaluate their activity. Method: Total flavonoids were extracted using ultrasonic extraction, and the inhibitory effect on the proliferation of lung cancer cells H1299 was investigated. Additionally, a preliminary study was conducted on the treatment of liver degeneration. Results: Using a 50% ethanol solution, ultrasonic treatment at 90°C for 50 minutes followed by reflux for 3 hours resulted in the highest total flavonoid extraction rate. The study showed that it has a certain inhibitory effect on the proliferation of lung cancer H1299 cells, with an IC50 value of approximately 200μg/mL measured by MTT assay. The treatment also showed therapeutic effects on liver degeneration.
Source: BIO Web of Conferences
Authors: Chunyang Wang, Shuang Fu, Ruidong Zhu, Hongyan Cao, Jiangyang Zhao
Institution: Qiqihar Medical University
Language: English
Topic: Medicinal Plant Research
Subfield: Plant Science
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4411923030