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The Improvement of General Condition and Immunity Function of CKD After Treatment With Bailing Capsule: A Randomized Clinical Trial

Year: 2025

Type: article

Study designs: Randomized Controlled Trial, Clinical Trial

Abstract: Background: The management of chronic kidney disease (CKD) presents significant challenges, with people often exploring new treatment strategies and medications in an attempt to slow disease progression. This study seeks to evaluate the efficacy of Bailing capsules in the treatment of CKD. Methods: A total of 148 patients with CKD and renal and spleen qi insufficiency were included in this study. The experimental group ( n = 87) received Bailing capsules in addition to the standard treatment, while the control group ( n = 61) received only the standard treatment. The study used both subjective and objective endpoints, including traditional Chinese medicine (TCM) syndrome scores, routine blood tests, biochemical markers, and lymphocyte counts, to evaluate the efficacy of Bailing capsules. Results: After statistical analysis, we found that the experimental group showed a significant decrease in TCM syndrome scores and in various biochemical indices, including reduced levels of cystatin C, 24‐h urine protein, bilirubin, gamma‐glutamyl transferase, and urinary red blood cell count ( p < 0.05). Additionally, the experimental group demonstrated an increase in white blood cell counts and regulation of immune function markers, such as CD3, CD4, and CD19 ( p < 0.05). Conclusion: After treatment, the relevant indicators of CKD showed significant improvement, and the patients’ immune function was also partially regulated. Notably, no significant adverse reactions were observed that would necessitate the termination of the study. Further investigation is required to gain a deeper understanding of these findings, particularly regarding the effects of Bailing capsules on immune function regulation in CKD. Trial Registration: Chinese Registry of Clinical Trials: ChiCTR‐IPR‐17014157

Source: International Journal of Clinical Practice

DOI: 10.1155/ijcp/7803666

Authors: Wanjia Chen, Rong Zheng, Xiaohong Cheng, Hongtao Yang, Yueyi Deng

Institutions: Longhua Hospital Shanghai University of Traditional Chinese Medicine, Shaanxi Provincial Hospital of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine

Language: English

Topic: Medical Research and Treatments

Subfield: Complementary and alternative medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,350