Optimized synthesis of aroyl-S,N-ketene acetals by omission of solubilizing alcohol cosolvents.
Year: 2025
Type: article
Abstract: -benzylbenzothiazolium salts in 1,4-dioxane at room temperature in short reaction time in 20-99% yield. This protocol represents a considerable improvement over the standard synthesis in 1,4-dioxane/ethanol mixtures at elevated temperatures.
Source: PubMed
DOI: 10.3762/bjoc.21.97
Authors: Julius Krenzer, Thomas J J Müller
Institution: Heinrich Heine University Düsseldorf
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W4411927808