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A rare case report of bilateral persistent pupillary membranes: Surgical intervention restoring vision in a young child

Year: 2025

Type: article

Abstract: Persistent pupillary membranes are a common congenital anomaly that usually resolves spontaneously in early infancy. However, bilateral extensive persistent pupillary membranes that entirely obscure the pupils, involve the visual axis, and adhere firmly to the lens are rarely reported. This report presents a rare case of bilateral extensive persistent pupillary membranes in a young child, resulting in severe visual axis obstruction and firm adhesion to the anterior lens capsule. Surgical removal led to a substantial improvement in visual acuity without complications. This case highlights the importance of early diagnosis and timely surgical intervention to restore vision and prevent long-term complications such as deprivation amblyopia.

Source: Science Progress

DOI: 10.1177/00368504251357183

Authors: Peng Lu, Wenwen Tian, Juan Wang, Yadong Wang

Institutions: Lanzhou University Second Hospital, Lanzhou University

Language: English

Topic: Ocular Disorders and Treatments

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,650