A non-invasive, reference region-based method for quantification of cerebral blood flow and oxygen metabolism using oxygen-15 labeled gases and positron emission tomography.
Year: 2025
Type: article
Abstract: Objectives: using PET and oxygen-15 labeled gases based on the steady-state method without invasive arterial blood sampling. Methods: were calculated without invasive arterial blood sampling. Results: calculated by the present method as compared with those obtained by the steady-state method with arterial blood sampling, indicating its validity. Simulation studies showed that errors in estimated values calculated by the present method were negligibly small for both conditions of misery perfusion and matched hypoperfusion. Conclusion: using PET and oxygen-15 labeled gases could be developed based on the steady-state method. This method can be used to investigate the pathophysiology of occlusive cerebrovascular disease.
Source: PubMed
Language: English
Subfield: Radiology, Nuclear Medicine and Imaging
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4411928299