The utility of quantitative 18F-FDG PET/CT-derived parameters as prognostic factors for predicting overall survival in radioiodine-refractory differentiated thyroid cancer.
Year: 2025
Type: article
Study design: Observational Study
Abstract: Objectives: F-FDG PET/CT metabolic parameters and overall survival (OS) in patients with radioiodine-refractory differentiated thyroid cancer (RAI-R DTC). Methods: F-FDG PET/CT imaging. Patients were monitored for disease progression and mortality for at least one-year post PET/CT imaging. Receiver operating characteristic (ROC) curves were used to establish cut-off values for predicting 5-year mortality, while the Kaplan-Meier method estimated the 5-year survival rate. Univariate and multivariate Cox regression analyses identified prognostic factors associated with OS. Results: and MTV emerged as independent predictors of OS. Conclusion: and MTV are independent prognostic factors for 5-year OS in patients with radioiodine-refractory DTC.
Source: PubMed
Authors: Mai Hong Son, Nguyen Thi Phuong, Le Ngoc Ha
Institution: 108 Military Central Hospital
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4411928306