Year: 2025
Type: article
Abstract: Aegle marmelos, commonly referred to as Bael, is renowned for its therapeutic potential, largely attributed to its rich content of bioactive flavonoids such as anthocyanins and betacyanins. These phytoconstituents are associated with notable antioxidant and anti-ulcer effects, primarily due to their capacity to neutralize free radicals. This investigation focuses on formulating a herbal toothpaste incorporating Aegle marmelos fruit extract, with the aim of aiding in the prevention and treatment of oral ulcers. The research encompassed both the development and comprehensive evaluation of the toothpaste formulation. Key quality parameters assessed included physical appearance, pH, consistency, foaming ability, sharpness of abrasive particles, spreadability, moisture level, and volatile matter content; all essential for product performance and consumer acceptability. The antimicrobial efficacy of the herbal toothpaste was examined through zone of inhibition studies against oral pathogens such as Bacillus subtilis and Staphylococcus aureus. Furthermore, the antioxidant activity was assessed through the DPPH free radical scavenging method, a well-established and commonly employed technique. Quantitative analysis of flavonoids was also performed, given their crucial role in therapeutic effectiveness. Overall, the results demonstrated that the toothpaste enriched with Aegle marmelos extract possesses significant antioxidant and antimicrobial activity, supporting its potential use as a natural remedy for managing and preventing mouth ulcers.
Institution: Bharati Vidyapeeth College of Pharmacy, Kolhapur
Language: English
Subfield: Complementary and alternative medicine
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4411930520