Work

A rare case of perforated giant mesenteric fibromatosis causing acute peritonitis

Year: 2025

Type: article

Abstract: Desmoid tumors (DT) are rare benign tumors originating from myofibroblasts in the mesentery. Although benign, DTs exhibit local invasion and recurrence and may present sporadically or with familial adenomatous polyposis (FAP) and Gardner's syndrome. The clinical presentation ranges from asymptomatic abdominal masses to severe complications such as bowel obstruction and perforation. This case report highlights a 46-year-old male with acute diffuse peritonitis due to perforation of a mesenteric fibromatosis (MF). Imaging revealed a large mesenteric mass causing bowel perforation, necessitating an urgent exploratory laparotomy. Surgical intervention entailed resection of the affected small bowel and mesentery with temporary stoma formation. Histopathology confirmed MF with negative margins, and the patient was discharged in stable condition. This case highlights the importance of a multidisciplinary approach in managing such complex cases, the challenges in diagnosing and treating intra-abdominal DTs, and the role of surgical resection with careful postoperative monitoring despite recurrence concerns.

Source: Journal of Surgical Case Reports

DOI: 10.1093/jscr/rjaf459

Authors: Mohanad Ibrahim, Ali Toffaha, Mahwish Khawar, Hamza A Abdul-Hafez, Mohamed Kurer

Institutions: Hamad Medical Corporation, Qatar University, An-Najah National University

Language: English

Topic: Soft tissue tumor case studies

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,000