Work

Coronary Artery Aneurysm Post Drug-Coated Balloon Angioplasty

Year: 2025

Type: article

Abstract: Drug-coated balloons have emerged as effective therapy for treating in-stent restenosis and de novo lesions. The animal studies have shown the mechanism of action of paclitaxel-coated balloon in coronary arteries which leads to medial necrosis that may explain the better angiographic remodelling observed with paclitaxel- as compared to sirolimus-coated balloons. However, in some cases, paclitaxel may cause adverse remodelling resulting in coronary artery aneurysm. Here, we report 4 cases of coronary artery aneurysm post paclitaxel-coated balloon angioplasty and discuss its possible mechanism, management, and potential implications for future practice.

Source: JACC Case Reports

DOI: 10.1016/j.jaccas.2025.103891

Authors: Aninka Saboe, Chetan Upadhya, Aloke Finn, Sandeep Basavarajaiah

Institutions: Dr. Hasan Sadikin General Hospital, Padjadjaran University, Glan Clwyd Hospital, CVPath Institute, Heartlands Hospital

Language: English

Topic: Coronary Interventions and Diagnostics

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $850