Work

Synthesis and structure of 6-bromo-2-(diethoxymethyl)-2-hydroxy-3-phenyl-2,3-dihydro-1 H -imidazo[1,2- a ]pyridin-4-ium chloride acetonitrile monosolvate

Year: 2025

Type: article

Abstract: In the title solvated molecular salt, C 18 H 22 BrN 2 O 3 + ·Cl − ·CH 3 CN, the imidazole ring is in envelope conformation and the pyridine and phenyl rings are oriented at a dihedral angle of 72.52 (5)°. In the crystal, O—H...Cl and N—H...Cl hydrogen bonds link the cations and anions into centrosymmetric tetramers enclosing R 2 4 (12) loops. Short Br...Cl [3.2313 (4) Å] and O...Cl [3.0490 (10) Å] contacts are observed. A Hirshfeld surface analysis of the structure indicates that the most important contributions for the crystal packing are from H...H (52.4%), H...C/C...H (12.1%), H...Br/Br...H (11.0%) and H...Cl/Cl...H (10.2%) interactions.

Source: Acta Crystallographica Section E Crystallographic Communications

DOI: 10.1107/s2056989025005778