Year: 2025
Type: article
Abstract: The current research was aimed at the synthesis of cis stilbene derivatives and testing their anti-cancer abilities. Various cis stilbenes substituted on the olefinic bridge were prepared and their characterizations were given using IR, NMR and MASS spectra. Sequences of the compounds that were tested regarding their cytotoxic effect on MCF-7 and HeLa cell lines. Of all the compounds, Compound 4a that was a methyl ester showed stronger activities against MCF-7 and HeLa cell lines with the IC50 value of 22.24 µm and 27.43 µm respectively
Source: Journal of Neonatal Surgery
Authors: Rathnakar Reddy Kotha, Anil Kuma Garige, Ramesh Alli, Pasunoori Sumanth Raj, Raparthi Vijay Kumar
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4412039899