Work

Association between leafy vegetable consumption and incidence of metabolic syndrome and its symptoms: a systematic review of prospective cohort and randomised control trials

Year: 2025

Type: review

Abstract: PURPOSE: Metabolic syndrome (MetS) is a combination of cardiometabolic risk factors that burden health systems worldwide. Vegetables contain substances that are essential in preventing chronic illnesses. However, the effect of leafy vegetable consumption on the incidence of MetS and its symptoms is unclear. We systematically reviewed the association between leafy vegetable consumption and the incidence of MetS and its symptoms. METHODS: The Web of Science, Scopus, and MEDLINE databases were searched for relevant publications until August 2023. Randomised control trials (RCT) and prospective cohort studies examining the effect of consumption of leafy vegetable/s on MetS or its components in healthy adults were included. RESULTS: Ten studies (eight RCTs and two cohort studies) were included. A reduction in systolic blood pressure after intervention with leafy vegetables was observed in one RCT, but no effect on blood pressure was reported in two RCTs. One cohort study reported reduced hypertension incidence with increased leafy vegetable intake. A reduction in blood glucose was observed in three RCTs, and two RCT found no change. One cohort study reported no association between leafy vegetable consumption and the incidence of type 2 diabetes. Two RCTs found no change in blood lipids. No trials assessing leafy vegetable consumption and obesity or MetS were found. CONCLUSION: Few studies evaluate the impact of leafy vegetable consumption on MetS and its symptoms. Beneficial effects are reported for blood glucose and blood pressure regulation, but the evidence is limited. More studies are needed to build a robust body of evidence.

Source: European Journal of Nutrition

DOI: 10.1007/s00394-025-03750-6

Authors: Esther N. Muriuki, Begum Celik, Gunter G. C. Kuhnle, Charlotte E. Mills

Institutions: Meru University of Science and Technology, University of Reading

Language: English

Topic: Nutritional Studies and Diet

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDGs: Good health and well-being, Zero hunger

Open Access status: hybrid

Estimated APC paid: $2,890