Work

Effects of dexmedetomidine and magnesium sulphate on controlled hypotension in FES surgeries

Year: 2025

Type: article

Study designs: Randomized Controlled Trial, Clinical Trial

Abstract: Rhinosinusitis often requires functional endoscopic sinus surgery (FESS) when medical management fails, and controlled hypotension minimizes blood loss and optimizes surgical conditions. Dexmedetomidine and magnesium sulphate are commonly used to achieve controlled hypotension. Therefore, it is of interest to compare their efficacy in FESS, randomizing 60 patients to receive either dexmedetomidine or magnesium sulphate. Intraoperative mean arterial pressure (MAP) was consistently lower in the dexmedetomidine group compared to the magnesium sulphate group (p<0.01). We show that dexmedetomidine demonstrated superior performance for controlled hypotension during FESS, potentially improving surgical conditions and patient outcomes.

Source: Bioinformation

DOI: 10.6026/973206300211211

Authors: Rajni Thakur, Shashi Kumari, Kirti Ahirwal, Sivasamy S

Institution: Gandhi Medical College

Language: English

Topic: Anesthesia and Sedative Agents

Subfield: Anesthesiology and Pain Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4412048069