Diffused Cerebral Microhemorrhage in a 15-Year-Old Boy with Ketoacidosis due to Undiagnosed Type Ι Diabetes Mellitus: A Case Report
Year: 2025
Type: article
Study design: Case Report
Abstract: Diabetes mellitus is a chronic endocrine disorder characterized by impaired regulation of blood glucose metabolism, leading to elevated blood sugar levels. This condition can result in a wide range of acute and chronic complications, significantly impacting patients' quality of life and overall health. Among the most severe acute complications are hyperosmolar hyperglycemic state (HHS) and diabetic ketoacidosis (DKA), both of which are life-threatening if not promptly treated. DKA, in particular, is more commonly associated with type 1 diabetes mellitus and is caused by a severe insulin deficiency, leading to metabolic acidosis, hyperglycemia, and the accumulation of ketones. Neurological complications, such as cerebral edema and cerebrovascular events, are also well-documented consequences of DKA, particularly in pediatric patients. However, intracerebral microhemorrhages, which are small bleeds within the brain tissue, have not been previously reported in the literature as a complication of juvenile DKA. This case report describes a 15-year-old boy who was newly diagnosed with type 1 diabetes mellitus and subsequently developed an intracerebral microhemorrhage following an episode of DKA. The report highlights the clinical presentation, diagnostic imaging findings, and management of this rare complication. Radiological evidence, including magnetic resonance imaging (MRI), revealed the presence of microhemorrhages, providing valuable insights into the potential neurological risks associated with DKA in pediatric patients. This case underscores the importance of vigilant monitoring for atypical complications in juvenile diabetes, particularly during acute metabolic crises like DKA. Further research is needed to understand the underlying mechanisms and risk factors for such rare neurological events in diabetic patients.
Author: Moein Masjedi
Institution: Shiraz University of Medical Sciences
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4412090425