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A Case of Osmotic Demyelination Syndrome: Diagnostic and Therapeutic Challenges

Year: 2025

Type: article

Abstract: Osmotic demyelination syndrome (ODS) is a rare anatomoclinical entity characterized by the destruction of myelin sheaths, most often secondary to very rapid correction of hyponatremia. Its clinical manifestations are highly variable, and its treatment is essentially based on prevention. We report here the case of ODS in a 54-year-old patient after correction of hyponatremia secondary to uncontrollable vomiting. The diagnosis of ODS was made by magnetic resonance imaging. The patient had more than one vulnerability factor that could explain the development of this syndrome. Even after restoration of fluid and electrolyte balance, she retained neuropsychiatric sequelae such as intermittent agitated confusion and ataxic gait.

Source: Scholars Journal of Medical Case Reports

DOI: 10.36347/sjmcr.2025.v13i07.001

Authors: Hajar Joulal, Lamia Essaadouni

Institution: Centre Hospitalier Universitaire Mohammed VI

Language: English

Topic: Electrolyte and hormonal disorders

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4412095388

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