Antibiotic use Period in Hospitalized Patients with Pneumonia: A Comprehensive Narrative Review
Year: 2025
Type: review
Abstract: Pneumonia continues to be a serious worldwide health issue, resulting inconsiderable morbidity and death in adults. This narrative analysis evaluates theideal length of antibiotic therapy in individuals with community-acquired pneumonia(CACP), hospital-acquired pneumonia (HACP), and ventilator-associated pneumonia(VASP). Present research indicates that less lengthy antimicrobial sessions aresuperior in both safety and effectiveness compared to longer sessions, particularlyin those suffering from mild to moderate community-acquired pneumonia (CACP),aligning with worldwide guideline suggestions. Data are insuffi cient for the ideallength of antibiotics in patients with HASP, necessitating individualized treatmentbased on the causal bacteria and clinical outcome. Lower sessions are seenequally effi cient as longer ones in managing VACP, except pneumonia induced bynon-fermenting Gram-negative bacteria; although, the length must be calibratedto account for potential increased recurrence rates alongside the establishedadvantages of shorter courses. Furthermore, the confi rmation of dependablebiomarkers or clinical indicators that discern people likely to gain advantages fromabbreviated treatment is essential. This review’s fi ndings may inform subsequentstudies on tailored antibiotic therapy for pneumonia to enhance results for patients
Source: Archives of Case Reports
Author: Abdulmajeed Alharbi
Institution: Taibah University
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4412098776