Work

Targeting granulosa cells with engineered DFO nanoparticles for the treatment of chemotherapy-induced premature ovarian failure

Year: 2025

Type: article

Abstract: experiments demonstrate that FSH-mPDA@DFO nanoparticles improve oocyte quantity and quality while restoring fertility and endocrine homeostasis in chemotherapy-induced POF mice. Collectively, FSH-mPDA@DFO nanoparticles hold a great potential for clinical prevention and treatment of POF patients.

Source: Theranostics

DOI: 10.7150/thno.115416

Authors: Tuo Zhang, Zhiyi Sheng, Jixian Zhang, Heng Zhang, Yan Zhang, Yunpeng Du, Xiangxin Liu, Zhu Hu, Qiyuan Luo, Guoqiang Xu, Yuan Gao, Meina He, Tengxiang Chen

Institutions: Guiyang Medical University, Shandong University, Hospital for Reproductive Medicine Affiliated to Shandong University

Language: English

Topic: Reproductive Biology and Fertility

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,671

OpenAlex ID: W4412100765

FWCI: 11.89

Cites: 46

Cited by: 14

Related to: 10