Work

[HDAC6 inhibitor ACY-738 induces apoptosis and autophagy in diffuse large B-cell lymphoma cells through P53 acetylation].

Year: 2025

Type: other

Abstract: The HDAC6 inhibitor ACY-738 induces mitochondria-dependent apoptosis and autophagy in DLBCL cells by acetylating P53, thereby inhibiting DLBCL cell proliferation.

Source: PubMed

DOI: 10.3760/cma.j.cn121090-20240826-00324

Authors: P J Jiang, J Y Liu, G C Yang, J R Li, X L Tian, S J Yang, J Wei, X Zhang

Institutions: Affiliated Hospital of North Sichuan Medical College, Army Medical University

Language: English

Topic: Histone Deacetylase Inhibitors Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Natural Science Foundation of China, Natural Science Foundation of Chongqing

Awards: G5931168143, G7757411359

OpenAlex ID: W4412110306

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