Work

Photocatalytic Deaminative Fluorination—Balancing Conflicting Chemical Properties

Year: 2025
Type: article
Abstract: The transformation of amines into alkyl fluorides is an important but highly underdeveloped process that would be useful for the synthesis of biologically active compounds. In this article, we describe the path to the development of deaminative fluorination under photocatalytic conditions. Through optimization studies, focusing on mechanistic complexities, we were able to determine crucial parameters influencing this reaction course.
Authors: Jakub Durka, Barbara Zielińska, Dorota Gryko
Language: English
Field: Chemistry
Open Access status: bronze
OpenAlex ID: W4412119500
FWCI: 0.289
Cites: 17
Cited by: 1
Related to: 10