Work

Reversible Lacosamide Interference in Electroconvulsive Therapy: A Case Report

Year: 2025

Type: article

Abstract: Ms. M is a 64-year-old female with a psychiatric history of schizoaffective disorder, bipolar type, and malignant catatonia, receiving biweekly maintenance electroconvulsive therapy (ECT). Her medical history includes hypertension, Parkinson’s disease, a reported seizure disorder, thyroid disease, hyperparathyroidism, gastroesophageal reflux disease, aortic valve replacement, and iron deficiency anemia. She was transferred to our academic tertiary care center from an outside hospital for ECT to treat presumed malignant catatonia. Psychoactive medications restarted at the time of her admission included carbidopa-levodopa 10–100 mg twice daily, lorazepam 2 mg by mouth every 8 hours, and lacosamide 200 mg twice daily. An EEG obtained at the outside hospital showed diffuse background slowing, consistent with mild global encephalopathy.

Source: Psychopharmacology Bulletin

DOI: 10.64719/pb.4541

Authors: Greg Miglis, Greg Noe, Molly Cinderella, Nona Nichols, Sahil Munjal

Institutions: Wake Forest University, Cone Health, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University

Language: English

Topic: Electroconvulsive Therapy Studies

Subfield: Psychiatry and Mental health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W4412157440

FWCI:

Cites:

Cited by:

Related to: 10