Providing Standardized Gene Nomenclature for Domestic Ungulate Scavenger Receptor Genes
Year: 2025
Type: article
Abstract: Scavenger Receptor (SCAR) genes are a heterogeneous group involved in innate immunity and immunomodulation. While standardized gene nomenclature is provided for model organism SCAR genes, ungulates have novel SCAR genes which have not been systematically classified. This study compares SCAR genes for five representative ungulate species which are selected based on their agricultural importance and representation. We identify and classify twenty-seven SCAR genes common to all species and provide standardized gene nomenclature for genes novel to these ungulate species. Notably, we provide standardized gene nomenclature for the previously studied Workshop Cluster 1 (WC1) genes which are absent in model organisms.
Source: PubMed
Authors: Jessica Cruz, Fiona McCarthy
Institution: University of Arizona
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
SDG: Zero hunger
Open Access status: green
OpenAlex ID: W4412157466