Work

Facile and green synthesis of [Pd(NHC)(η 3 -R-allyl)Cl] complexes and their anticancer activity

Year: 2025

Type: article

Abstract: anticancer activity against several human cancer cell lines. Most complexes, except those with highly bulky and lipophilic ligands, showed excellent cytotoxicity-comparable to cisplatin in cisplatin-sensitive tumors and up to 100 times more potent than the reference drug in highly aggressive or resistant cancers. Structural variations such as the type of palladium fragment or imidazol ring saturation had minimal impact on cytotoxic performance.

Source: Dalton Transactions

DOI: 10.1039/d5dt01326g