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IBS: Pathophysiology and Management Challenges

Year: 2025

Type: article

Abstract: Irritable Bowel Syndrome (IBS) is a widespread functional gastrointestinal ailment with chronic abdominal pain, change in bowel movements, and reduced quality of life as hallmarks. Unlike organic diseases, IBS is idiopathic—diagnosed in the absence of structural or biochemical disturbances, which makes disease management more difficult. The causes of IBS are heterogeneous: dysregulation of gut-brain axis, visceral hypersensitivity, motility disorders, changes in microbiome, and psychosocial aspects contribute to it. This article explains causes of IBS, symptomatology, diagnostic criteria, and treatment options multidisciplinary with a focus on tailored dietary intervention, medication, psychotherapy, as well as alternative methods.

Source: African Journal of Sciences and Traditional Medicine

DOI: 10.58578/ajstm.v2i2.5641

Authors: Muhammad Akram, Isaac John Umaru, Abid Mahmood, Mohammed Khudhair Hasan, Hind A. Abdulghafoor, Fahad Said Khan, Fethi Ahmet Ozdemir, Gaweł Sołowski, Jaouher Ben Ali, Jehan Mohammed Jehan Mohammed Al-Musawi

Institutions: Government College University, Faisalabad, Federal University Wukari, University of Manara, University Of Fallujah, University of Poonch Rawalakot, Bingöl University, Tunis University, University of Kufa

Language: English

Topic: Gastrointestinal motility and disorders

Subfield: Gastroenterology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4412351825

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