Work

Quantitative estimation of disposition index from postprandial glucose data across the spectrum of glucose tolerance

Year: 2025

Type: article

Abstract: The advent of continuous glucose monitoring (CGM) in non-insulin-treated individuals raises the possibility of quantifying disposition index (DI), a key metric of β-cell function usually assessed in research settings, in outpatients. A method for DI estimation from postprandial glucose data only (DI G ) was developed and validated against a reference. DI G can be used to assess therapy effectiveness and degree of glucose tolerance in non-insulin-treated individuals, paving the way for its quantification in real-life conditions from CGM devices.

Source: American Journal of Physiology-Endocrinology and Metabolism

DOI: 10.1152/ajpendo.00407.2024

Authors: Michele Schiavon, Adrian Vella, Chiara Dalla Man

Institutions: University of Padua, Mayo Clinic

Language: English

Topic: Diabetes Management and Research

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: Ministero dell'Università e della Ricerca, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases