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Formulation and Assessment of Rapidly Disintegrating Tablets of Empagliflozin by Enhancing Dissolution Rate and Bioavailability

Year: 2025

Type: article

Abstract: This study developed and evaluated mouth disintegrating tablets (MDTs) of Empagliflozin to enhance patient compliance and rapid drug onset. Using UV spectrophotometry (λmax 225nm in 0.1NHCl), MDTs were prepared via direct compression with superdisintegrants SSG, Crospovidone, and Croscarmellose sodium. All formulations met pharmacopeial standards. Batch F-6 with Crospovidone showed the best performance, releasing 99% of the drug within 30 minutes. The findings confirm the effectiveness of a minimal-excipient, direct compression method for efficient Empagliflozin delivery.

Source: International journal of research in pharmacy and life sciences.

DOI: 10.30904/j.ijrpls.2025.4820

Authors: Sai Tharun T P, Anjaneyulu Dr. V, Vijay Kumar Gampa

Language: English

Topic: Drug Solubulity and Delivery Systems

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4412371755

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