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Formulation and Evaluation of Ornidazole Topical Emulgels

Year: 2025

Type: article

Abstract: This study focused on developing and evaluating Ornidazole-based emulgel formulations for topical use. A UV calibration curve confirmed the drug’s λmax at 335 nm, while FTIR and DSC verified its purity and stability with excipients. All formulations showed suitable pH (5.24–6.0) for skin application. Among them, formulation F3 exhibited the best spreadability, viscosity, and drug release (93.2% in 6 hours), along with the highest antimicrobial activity (48.48% inhibition). F3 also demonstrated good drug content uniformity and skin compatibility. Overall, F3 proved to be a promising topical delivery system for Ornidazole, warranting further clinical investigation.

Source: International journal of pharmacy and natural medicines.

DOI: 10.30904/j.ijpnm.2025.4819

Authors: Shariq Mohd, Ramesh K, Vijay kumar Gampa, Nagaraju I

Language: English

Topic: Advancements in Transdermal Drug Delivery

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4412371788

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