Work

Ciprofloxacin and Metronidazole As Rare Culprits of Drug-Induced Immune Thrombocytopenia in the Setting of Diverticulitis Treatment

Year: 2025

Type: article

Abstract: Drug-induced immune thrombocytopenia (DITP) is a syndrome in which antibodies bind to platelets only in the presence of a drug, leading to platelet destruction. A variety of medications, herbs, vaccines, and foods have been commonly associated with DITP. Here, we present a case of DITP in a 61-year-old female who was receiving two widely prescribed antibiotics, ciprofloxacin and metronidazole, which are not commonly linked to DITP. The patient developed thrombocytopenia within 24 hours of initiating these antibiotics, and her platelet count rapidly normalized following discontinuation of the drugs. Severe thrombocytopenia can lead to life-threatening bleeding; therefore, it is imperative that treating providers rule out alternative causes of thrombocytopenia and promptly discontinue any potential offending agents.

Source: Cureus

DOI: 10.7759/cureus.87835

Authors: Jody W Tai, Ericka H Young, Vivek D Shah, Jarred P Reed

Institutions: Los Angeles Medical Center, Olive View-UCLA Medical Center, University of California, Los Angeles

Language: English

Topic: Platelet Disorders and Treatments

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4412373252