Work

Toward high-density streptavidin arrays on DNA origami nanostructures

Year: 2025

Type: article

Abstract: Streptavidin binding to DNA origami-supported high-density biotin arrays is investigated for selected experimental parameters. While bidentate binding and steric hindrance can be minimized, molecular crowding limits the binding yields in 2D arrays.

Source: RSC Advances

DOI: 10.1039/d5ra03393d

Authors: Lukas Rabbe, Emilia Tomm, Guido Grundmeier, Adrian Keller

Institution: Paderborn University

Language: English

Topic: Advanced biosensing and bioanalysis techniques

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $1,042

Funders: European Commission, European Innovation Council and Small and Medium-sized Enterprises Executive Agency