Metal- and base-free spirocyclization of alkylidene oxindoles via photo- and mechanochemically-generated nitrile ylides and nitrile imines as 1,3-dipoles
Year: 2025
Type: article
Abstract: We report an efficient, metal- and base-free synthesis of spiro[pyrrolidine-3,3′-oxindoles] and spiro[indoline-3,3′-pyrazol]-2-ones via 3 + 2 cycloadditions of in situ generated nitrile ylides and nitrile imines with alkylidene oxindoles.
Source: Organic Chemistry Frontiers
DOI: 10.1039/d5qo00851d
Authors: Shweta Singh, Roopam Pandey, Varun Christopher, Mahesh Kumar Ravva, Rakesh Ganguly, Subhabrata Sen
Institutions: Shiv Nadar University, SRM University
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: hybrid
Funder: Shiv Nadar Foundation
OpenAlex ID: W4412410438