Supplementary Figure S3 from JAB-3312, a Potent Allosteric SHP2 Inhibitor That Enhances the Efficacy of RTK/RAS/MAPK and PD-1 Blockade Therapies
Year: 2025
Type: supplementary-materials
Abstract: Supplementary Figure S3. Body weight change of KRASG12C mutant tumors. A-E. Body weight change of SW837 (A), MIA PaCa-2 (B), CR6243 (C), CR6256 (D), and LU6405 (E) xenograft models during the treatment of JAB-3312, glecirasib, and the two-drug combination. Mean ± SEM was shown.
Authors: Di Kang, Yanping Wang, Yiwei Lin, Wen Wee Ma, Daniel Morgensztern, Konstantinos Leventakos, Chao Bi, Yuli Ding, Jing Xiong, Man Yan, Xin Sun, Peng Wang, Cunbo Ma, Yinxiang Wang
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4412417888