Work

An Open-Source Browser-Based Nonlinear Model Predictive Controller for Type 1 Diabetes

Year: 2025

Type: article

Abstract: We provide an open-source implementation of the NMPC algorithm for closed-loop insulin therapy presented by Hovorka et. al. in the seminal paper from 2004. An extended Kalman filter is added as observer, since specifics on state estimation have been omitted in the original paper. The controller is now part of the TypeScript-based closed-loop diabetes simulator LT1, which also comprises a library of models describing CGM sensors, infusion pumps, and patient physiology. The controller can thus be extensively tested in various closed-loop configurations. Also, the graphical user interface enables its integration in educational tools.

Source: IFAC-PapersOnLine

DOI: 10.1016/j.ifacol.2025.06.025

Authors: Lara Hauser, John Bagterp Jørgensen, Heiko Peuscher

Institutions: Technische Hochschule Ulm, Technical University of Denmark

Language: English

Topic: Diabetes Management and Research

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4412437106

FWCI:

Cites: 10

Cited by:

Related to: 10