Work

Managing Blood Glucose in Premature Neonates via Parenteral Nutrition: In-silico Evaluation

Year: 2025

Type: article

Abstract: Prometeus (Preterm Brain-Oxygenation and Metabolic EU-Sensing: Feed the Brain) develops innovative technology for personalized nutrition in premature neonates. Central to this is the Nutritional Clinical Advisor, an adaptive algorithm providing optimal parenteral nutrition plans to enhance brain oxygenation. This study tests a closed-loop PID controller for regulating glucose levels in virtual neonates born preterm, offering insights into its effectiveness and guiding future NCA development to support neonatal care.

Source: IFAC-PapersOnLine

DOI: 10.1016/j.ifacol.2025.06.001

Authors: Arthur Bertachi, Hadija Marchiori, Chiara Dalla Man, Josep Vehi

Institutions: Universidade Tecnológica Federal do Paraná, Universitat de Girona, University of Padua, Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas

Language: English

Topic: Diabetes Management and Research

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: Conselho Nacional de Desenvolvimento Científico e Tecnológico