Work

Development of cell-based assay for detecting replication-competent adeno-associated virus by qPCR

Year: 2025

Type: article

Abstract: vector genomes. The same approach for rcAAV method development can be expanded to all other AAV serotypes, providing means for substantially improving process development and product safety.

Source: Molecular Therapy — Methods & Clinical Development

DOI: 10.1016/j.omtm.2025.101529

Authors: Aishwarya Shevade, John S. Reeves, Hanne Bak, Andrew D. Tustian

Institution: Regeneron (United States)

Language: English

Topic: Virus-based gene therapy research

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,900

Funder: Regeneron Pharmaceuticals

OpenAlex ID: W4412447147

FWCI: 1.104

Cites: 28

Cited by: 2

Related to: 10