AAV6 vectors provide superior gene transfer compared to AAV9 vectors following intramyocardial administration
Year: 2025
Type: article
Abstract: assays, thereby facilitating the development of more potent AAV variants for cardio-selective delivery methods.
Authors: Jianan Wang, Timo Jonker, Aina Cervera-Barea, Zhenyu Dong, Ruud N. Visser, Evelien E. Birza, Arie R. Boender, Mischa Klerk, Yuting Yang, Joyce Visser, Marlijn S. Jansen, Tom C. Grootswagers, Cindy I. Bart, Saskia C.A. de Jager, Silke Schrödel, Christian Thirion, Osne F. Kirzner, Hanno L. Tan, Antoine A.F. de Vries, Joost P.G. Sluijter, Klaus Neef, Joris R. de Groot, Vincent M. Christoffels, Gerard J.J. Boink
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $3,900
Funders: Health~Holland, Nederlandse Organisatie voor Wetenschappelijk Onderzoek, Horizon 2020 Framework Programme, European Research Council, Horizon 2020, Moonshot Research and Development Program, H2020 Marie Skłodowska-Curie Actions, Eurostars, HORIZON EUROPE Marie Sklodowska-Curie Actions, HORIZON EUROPE European Innovation Council, HORIZON EUROPE European Research Council
Awards: G1522548176, G2315799801, G2808490425, G3642840513, Pacing the heart; studying the underlying principles of biological pacemakers, G4060467852, G5264237701, Technology Of Protein delivery in Extracellular Vesicle-induced Cardiac Repair, Transcription Factor Gene Therapy for Bradyarrhythmias, G5926214448, G5951669680, G6925974117, G7013656764, G8131308246, G8203862318, G8210713347, G877780602, Local Training Network on REgenerative medicine and Stem Cell technology in UtrEcht
OpenAlex ID: W4412458871