The risk of alcohol use disorders in young adults with hyperactivity/inattention problems in early adolescence: UK birth cohort study
Year: 2025
Type: article
Study design: Observational Study
Abstract: PURPOSE: This study aimed to examine the association between hyperactivity/inattention problems in early adolescence and the risk of alcohol use disorders (AUDs) in young adulthood. METHODS: We used data from the Avon Longitudinal Study of Parents and Children (ALSPAC), a population-based prospective cohort based in Bristol, United Kingdom. Logistic regression analyses were used to examine associations. E-values (E) were calculated to estimate the potential impact of unmeasured confounding. RESULTS: Hyperactivity/ inattention problems in early adolescence were associated with a 1.75-fold increased risk of any AUDs (OR = 1.75, 95 % CI: 1.20-2.56; E = 2.90, CI: 1.69) and a 4-fold increased risk of severe AUD at age 24 (OR = 4.35, 95 % CI: 2.00 - 9.47; E = 8.17, CI: 3.58). We also observed a 2.09 (OR = 2.09, 95 % CI: 1.24-3.53; E = 3.60, CI: 1.79) and 1.63-fold (OR = 1.63, 95 % CI: 1.07 - 2.49; E = 2.64, CI: 1.34) increased risk of alcohol dependence symptoms and alcohol abuse symptoms, respectively, at age 24 among those with hyperactivity problems at age 11. These associations did not differ by sex (P > 0.05). CONCLUSIONS: Hyperactivity/ inattention problems in early adolescence were associated with an increased risk of AUDs in adulthood. Unmeasured confounders were unlikely to alter the observed associations. Early identification and intervention for behavioural problems may help reduce the risk of AUDs later in life.
Source: Annals of Epidemiology
Authors: Berihun Dachew, Getinet Ayano, Rosa Alati
Institutions: Curtin University, The University of Queensland
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,820
OpenAlex ID: W4412459709