Work

Design, synthesis, and anti-plasmodial profiling of oxalamide-linked 4-aminoquinoline-phthalimide hybrids

Year: 2025

Type: article

Abstract: value of 0.037 μM. Inhibition of hemozoin formation proved to be the primary mechanism of action of the most promising compound of the series with superior binding affinity toward heme compared to CQ.

Source: RSC Medicinal Chemistry

DOI: 10.1039/d5md00425j

Authors: Nikita Gupta, Kewal Kumar, Raghu Raj, Vipan Kumar

Institutions: Guru Nanak Dev University, Maharaja Ranjit Singh Punjab Technical University

Language: English

Topic: Malaria Research and Control

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: Department of Science and Technology, Ministry of Science and Technology, India

Award: G2378552740

OpenAlex ID: W4412472147

FWCI: 1.699

Cites: 28

Cited by: 2

Related to: 10