Staphylococcal Toxiderma in an 18-Month-Old Infant Evolving to Lyell’s Syndrome: A Case Report
Year: 2025
Type: article
Study design: Case Report
Abstract: Staphylococcal toxidermia is a rare but potentially life-threatening condition in children, occasionally evolving toward a toxic epidermal necrolysis-like presentation (1). Case Presentation: We report the case of an 18-month-old female infant presenting with fever and impetiginous lesions rapidly evolving into a generalized exfoliative eruption suggestive of Lyell’s syndrome. Neurological deterioration was observed. Blood cultures were negative, but the clinical features were compatible with staphylococcal scalded skin syndrome (SSSS). The patient was treated with intravenous vancomycin and a 5-day course of immunoglobulins at 0.4 g/kg/day, resulting in a favorable outcome. Conclusion: This case highlights the importance of early recognition of severe staphylococcal skin syndromes and the potential benefit of adjunctive immunoglobulin therapy in extensive cases with neurological involvement.
Institution: Centre Hospitalier Universitaire Ibn Rochd
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4412474294