Work

Microbial signatures and ARGs profiles in two coastal ecosystems of Shenzhen under distinct anthropogenic influences

Year: 2025

Type: article

Abstract: Megacity coastal areas, under human activity pressure, are recognized as reservoirs of human pathogens and antibiotic resistance genes (ARGs). However, the dynamics and potential health risks under different anthropogenic stressors remain unclear. In this study, surface seawaters were sampled from Shenzhen's western (SZW) and eastern (SZE) coasts, considering the influences of intensive population and industrial activities, as well as tourism and recreational activities. This study revealed distinct microbiomes and selective enrichments of heavy metals and ARGs in SZW and SZE areas, with correlations between most ARGs with intl1 . The microbiome-ARG co-occurrence network of SZE was more complex, containing diverse human pathogens and ARGs, highlighting health risks even in low-population density recreational areas. Hub pathogens and ARGs may contribute to shaping these networks, and have the potential to serve as new indicators for different coastal human disturbances. These findings aid in developing strategies for urban coastal sustainability and mitigating antimicrobial resistance.

Source: iScience

DOI: 10.1016/j.isci.2025.113133

Authors: Xindi Lu, Shan Yu, Lijuan Zhang, Siwei Liu, Hailong Lu

Institution: Peking University

Language: English

Topic: Pharmaceutical and Antibiotic Environmental Impacts

Subfield: Pollution

Field: Environmental Science

Domain: Physical Sciences

SDGs: Good health and well-being, Sustainable cities and communities, Life below water

Open Access status: gold

Estimated APC paid: $3,240