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When Teratomas Turn Brutal: From Indolent to Invasive in Stage IIIB Ovarian Squamous Cell Carcinoma

Year: 2025

Type: article

Abstract: This case report identifies a 74-year-old female with Stage IIIB ovarian cancer, with a specific diagnosis of squamous cell carcinoma arising in a mature teratoma. She sustained surgical cytoreduction that included gynecologic oncology, general surgery, and urology. Post-operative care was coordinated to deal with early complications and recovery by working together as a multidisciplinary team. The case delves into the rare pathophysiology of malignant transformation in teratoma related to ovarian cancer, the principles of staging, and current treatment methods. This case further emphasizes the prognostic importance of mesoappendiceal involvement, a factor that independently contributes to upstaging and indicates a higher risk for recurrence. Follow-up care consisted of advanced imaging, options for adjuvant chemotherapy, and genetic counseling/referral for testing. This case report recognizes that early identification, the importance of multidisciplinary care, and follow-up based on rare ovarian malignancies are found in each of these issues.

Source: Cureus

DOI: 10.7759/cureus.88090

Authors: Nasim Salimiaghdam, Ahmed Mustafa, Afshin Hamidi, Alsu Ramazanova, Emily Chen

Institutions: Capital Health, Arrowhead Regional Medical Center

Language: English

Topic: Ovarian cancer diagnosis and treatment

Subfield: Reproductive Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4412479758