Nephroprotective impact of royal jelly against rhabdomyolysis-induced kidney damage in rats.
Year: 2025
Type: article
Abstract: Objectives: The current work aimed at studying the impact of royal jelly on kidney damage caused by rhabdomyolysis in male rats. Materials and Methods: 40 male rats were randomly assigned to five groups of eight: control, rhabdomyolysis, and rhabdomyolysis, administered with three doses of royal jelly (RJ) (100, 200, and 400 mg/kg) for seven days. On the fifth day, we injected glycerol intramuscularly to induce rhabdomyolysis. Researchers examined serum biochemical parameters, inflammation, oxidative stress, apoptosis, and kidney tissue injury. Results: by RJ at 100 and 400 mg/kg doses. Conclusion: Royal jelly safeguards the kidney from rhabdomyolysis-related damage, primarily through its anti-oxidant, anti-apoptotic, and anti-inflammatory effects.
Source: PubMed
Authors: Ahmad Reza Aminian, Mohammad Taghi Khoshniat, Abolfazl Khajavi Rad, Maryam Mahmoudabady, Mohammad Hossein Rigi, Sara Hosseinian
Institution: Mashhad University of Medical Sciences
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4412486993