Year: 2025
Type: article
Abstract: The EuPRAXIA project is a European initiative aimed at developing groundbreaking, ultra-compact accelerator research infrastructures based on novel plasma acceleration concepts. The EuPRAXIA@SPARC_LAB facility, located in the Italian National Institute for Nuclear Physics-Frascati National Laboratory, will be the first operating Free Electron Laser facility of EuPRAXIA, based on an accelerator module driven by an electron bunch driver. The Free Electron Laser will produce ultra-short photon pulses in the soft X-ray region. The photons will be delivered to an endstation, called AQUA, to perform a wide range of experiments in atomic and molecular physics, chemistry, and life sciences for both academic and industrial users. Thanks to its wavelength, which falls within the so-called 'water window', AQUA will be particularly well-suited for coherent imaging and ion spectroscopy measurements on biological samples at room temperature in a fully hydrated environment. This unique capability opens up innovative experimental schemes for studying biological systems in states that closely resemble their physiological conditions. This paper presents numerical simulations of coherent diffraction imaging and Coulomb explosion imaging experiments, anticipating future studies at AQUA on biological samples.
Source: European Biophysics Journal
Institutions: University of Rome Tor Vergata, Uppsala University, European X-Ray Free-Electron Laser, Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali di Frascati, AREA Science Park, Elettra-Sincrotrone Trieste S.C.p.A., Rome International Center for Materials Science, Deutsches Elektronen-Synchrotron DESY, Center for Free-Electron Laser Science
Language: English
Subfield: Radiation
Field: Physics and Astronomy
Domain: Physical Sciences
Open Access status: hybrid
Estimated APC paid: $2,490
Funders: European Commission, Bundesministerium für Bildung und Forschung, Vetenskapsrådet, Ministero degli Affari Esteri e della Cooperazione Internazionale, Helmholtz Association, Röntgen-Ångström Cluster, Scheme for Promotion of Academic and Research Collaboration, HORIZON EUROPE Framework Programme, Deutsches Elektronen-Synchrotron, Horizon 2020, HORIZON EUROPE Marie Sklodowska-Curie Actions
Awards: The Next Generation MS SPIDoc’s, EuPRAXIA Preparatory Phase Project, G434337789, Verbundprojekt 05K2022 - 2021-05988 SAXFELS: Kleinwinkel-Röntgen-Freie-Elektronenlaser-Streuung, G5404260858, G5643668128, G5853244934, G6523014278, G6536968873, Solving the orientation problem in Single Particle Imaging using XFEL, G712881263, G8315843821, SAXFELS, G869003648, NAISS, FIXED: Fluorescent Incoherent X-ray Emission and Diffraction to determine protein structures
OpenAlex ID: W4412487729