Work

Piperidine and valproic acid hybrid compound (F2S4-p-VPA) outperforms methotrexate as anti-proliferative and cells migration inhibition

Year: 2025

Type: article

Abstract: The hybrid compound F2S4-p-VPA, comprising piperidine and valproic acid moities, demonstrated cytotoxic effect and effectively inhibit cellular migration against glioblastoma multiforme (GBM) cells.

Source: RSC Advances

DOI: 10.1039/d5ra01365h

Authors: Martha Cecilia Rosales Hernández, Raúl Horacio Camarillo López, Marycruz Olvera-Valdez, Leticia Guadalupe Fragoso Morales, Itzia Irene Padilla Martínez, Mónica Adriana Torres Ramos, Marycarmen Godínez Victoria, Raúl Flores Mejía, José Correa Basurto

Institutions: Instituto Politécnico Nacional, Instituto Nacional de Neurología y Neurocirugía, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional

Language: English

Topic: Synthesis and biological activity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,042

OpenAlex ID: W4412488743

FWCI: 0.292

Cites: 74

Cited by: 1

Related to: 10