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Enhanced On-Demand Antibacterial Platform Based on Triboelectric-Nanogenerator-Induced Electrical Stimulation of Cu2S Substrates

Year: 2025

Type: article

Abstract: High Resolution Image Download MS PowerPoint Slide Triboelectric nanogenerators (TENGs) offer a sustainable, battery-free solution for wearable electronics by converting motion into energy. However, direct skin contact poses bacterial contamination risks, requiring advanced antibacterial strategies. This study developed an on-demand antibacterial platform based on TENG-induced electrical stimulation of Cu 2 S substrates, benchmarked against Cu 2 O. Submicron-structured Cu 2 S layers were fabricated via a novel sulfurization method applied to electrodeposited Cu 2 O layers on fluorine-doped tin oxide (FTO) substrates. The resulting Cu 2 S and Cu 2 O thin films were integrated into a single-electrode TENG system, and their antibacterial efficacy was evaluated under electrical stimulation driven by a Kapton–FTO TENG.Experimental results revealed that a 10-min finger-tapping-generated electrical current from the TENG significantly enhanced the antibacterial performance of Cu 2 S, increasing its efficacy against bacterial models of Staphylococcus aureus and Escherichia coli from 25% to 70% and from 55% to 100%, respectively. In contrast, Cu 2 O demonstrated high intrinsic antibacterial activity with minimal improvement under TENG stimulation. The enhanced response of Cu 2 S was attributed to a ∼115% increase in Cu ion release, significantly higher than the ∼17% increase observed for Cu 2 O. This enhanced performance was further attributed to intensified electrostatic interactions between positively charged electrode surfaces and negatively charged bacterial membranes, leading to membrane interruption and bacterial death. Additionally, electron capture from bacterial electron transport chains heightened oxidative stress, disrupted energy metabolism, and further enhanced antibacterial effects. These findings accentuate the potential for integrating TENGs into biomedical applications, particularly in advanced wearable devices, to provide inherent antibacterial functionality for safe and effective direct human contact.

Source: ACS Applied Materials & Interfaces

DOI: 10.1021/acsami.5c04717

Authors: Marziyeh Jannesari, Leyla Shooshtari, Nima Mohamadbeigi, Niall J. English, Raheleh Mohammadpour

Institutions: University College Dublin, Sharif University of Technology, Materials and Energy Research Center

Language: English

Topic: Advanced Sensor and Energy Harvesting Materials

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,500