Immunotherapy and combination treatments for triple-negative breast cancer: a Scopus bibliometric perspective
Year: 2025
Type: article
Abstract: BACKGROUND: Immunotherapy, a cornerstone treatment for triple-negative breast cancer (TNBC), has several limitations as a monotherapy. Global research is actively investigating effective combinatorial immunotherapy treatments for TNBC. Aim: This study aimed to elucidate an overview and research hot spots of immunotherapy and its combinatorial regimens in TNBC management for the past 5 years. MATERIALS & METHODS: Publications were retrieved from Scopus from 2019 to 2023 and analyzed using Harzing's Publish or Perish, Microsoft Excel, and VOSviewer. RESULTS: The study included a total of 1,818 publications, demonstrating increased publication trends over the years. The most productive continent, country, and journal were Asia (TP = 957), the United States (TP = 653), and Cancers (TP = 123), respectively. The United States and China exhibited the most dynamic inter-country collaboration, evidenced by the highest link strength (69). The United States emerged as the most influential country, recording the highest TLS (520). The analysis of co-occurrence author keywords revealed ICIs, PD-L1, and TME as research hot spots. The thorough integration of knowledge and research on these hot spots may offer an alternative in the management of TNBC. CONCLUSION: It is imperative to identify combinatorial immunotherapy treatments in order to have better cancer management.
Source: Future Oncology
Institutions: Universiti Sains Malaysia, Sultan Zainal Abidin University
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4412510669